Protein Modification Reagents
eMolecules 1919045-00-3 | m-PEG3-Sulfone-PEG2-OH | Broadpharm | MFCD29918251 | 344.420 | C13H28O8S | 98.000 | COCCOCCOCCS(=O)(=O)CCOCCOCCO | 1g | 309209074
m-PEG3-Sulfone-PEG2-OH | Broadpharm | 1919045-00-3 | MFCD29918251 | 344.420 | C13H28O8S | 98.000 | COCCOCCOCCS(=O)(=O)CCOCCOCCO | 1g | 309209074
![eMolecules 1263166-93-3 | endo-BCN-PEG2-amine | Broadpharm | MFCD19705418 | 324.421 | C17H28N2O4 | 95.000 | NCCOCCOCCNC(=O)OC[C@@H]1[C@@H]2CCC#CCC[C@H]12 | 500mg | 533795522](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502203458.JPG-250.jpg)
eMolecules 1263166-93-3 | endo-BCN-PEG2-amine | Broadpharm | MFCD19705418 | 324.421 | C17H28N2O4 | 95.000 | NCCOCCOCCNC(=O)OC[C@@H]1[C@@H]2CCC#CCC[C@H]12 | 500mg | 533795522
endo-BCN-PEG2-amine | Broadpharm | 1263166-93-3 | MFCD19705418 | 324.421 | C17H28N2O4 | 95.000 | NCCOCCOCCNC(=O)OC[C@@H]1[C@@H]2CCC#CCC[C@H]12 | 500mg | 533795522
eMolecules 2183440-35-7 | N-(acid-PEG3)-N-bis(PEG3-amine) | Broadpharm571.709 | C25H53N3O11 | 95.000 | NCCOCCOCCOCCN(CCOCCOCCOCCN)CCOCCOCCOCCC(O)=O | 250mg | 374905433
N-(acid-PEG3)-N-bis(PEG3-amine) | Broadpharm | 2183440-35-7571.709 | C25H53N3O11 | 95.000 | NCCOCCOCCOCCN(CCOCCOCCOCCN)CCOCCOCCOCCC(O)=O | 250mg | 374905433
eMolecules Fluorescein-PEG4-azide | 1454662-54-4 | MFCD30527398 | 25mg
Broadpharm | Fluorescein-PEG4-azide | 25mg | 387754546 | BP-23405 | 95.000 | 1454662-54-4 | MFCD30527398 | 651.690 | C31H33N5O9S
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eMolecules Building Block Tool
eMolecules 2128735-20-4 | N-Mal-N-bis(PEG2-amine) TFA salt | Broadpharm430.502 | C19H34N4O7 | 98.000 | NCCOCCOCCN(CCOCCOCCN)C(=O)CCN1C(=O)C=CC1=O | 250mg | 354974835
N-Mal-N-bis(PEG2-amine) TFA salt | Broadpharm | 2128735-20-4430.502 | C19H34N4O7 | 98.000 | NCCOCCOCCN(CCOCCOCCN)C(=O)CCN1C(=O)C=CC1=O | 250mg | 354974835
Cayman Chemical dG-PEG 2000 250mg
A PEGylated derivative of DSG; LNPs containing DSG-mPEG(2000) and encapsulating an imidazoquinoline TLR7 and TLR8 agonist and a peptide antigen EAch conjugated to PGA increase the activation of dendritic cells, macrophages, and B cells in the draining lymph node and dendritic cells and B cells in the spleen in mice compared to the non-LNP-encapsulated PGA-conjugated TLR7/8 agonist and peptide antigen.
Cayman Chemical PEG 2000-dPE 50mg
A PEGylated form of DSPE; has been used in the generation of micelles and in combination with other lipids in the formation of liposomes; liposomes containing DSPE-mPEG(2000) and encapsulating doxorubicin and quercetin reduce tumor growth in an MCF-7/adr multidrug-resistant breast cancer mouse xenograft model
Medchemexpress LLC 2-[2-[2-[2-(2-Bromoethoxy)ethoxy]ethoxy]ethoxy]oxane | 1803547-60-5 | 97.0% | 341.24 | 250 MG
Br-PEG4-THP is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. PROTACs are designed with two distinct ligands connected by a linker; one targets an E3 ubiquitin ligase and the other targets a specific protein. This mechanism leverages the intracellular ubiquitin-proteasome system to facilitate the selective degradation of target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Exploits ubiquitin-proteasome system
- Selectively degrades target proteins
eMolecules 1345337-22-5 | N-Boc-PEG8-alcohol | Broadpharm | MFCD28976659 | 469.572 | C21H43NO10 | 98.000 | CC(C)(C)OC(=O)NCCOCCOCCOCCOCCOCCOCCOCCO | 1g | 296213525
N-Boc-PEG8-alcohol | Broadpharm | 1345337-22-5 | MFCD28976659 | 469.572 | C21H43NO10 | 98.000 | CC(C)(C)OC(=O)NCCOCCOCCOCCOCCOCCOCCOCCO | 1g | 296213525
Medchemexpress LLC m-PEG2-CH2CH2COOH | 209542-49-4 | MFCD20646047 | ≥97.0% | 192.21 g/mol | C8H16O5 | 5 G
m-PEG2-CH2CH2COOH is a PEG-based PROTAC linker used in the synthesis of proteolysis targeting chimeras (PROTACs). It provides a short, flexible polyethylene glycol spacer terminating in a carboxylic acid group for conjugation and linkage in medicinal chemistry research.
- Short PEG2 spacer terminating in a carboxylic acid for conjugation.
- Suitable for use as a PROTAC linker in medicinal chemistry applications.
- Available in multiple sizes for synthesis scale flexibility, including 5 G.
- Characterized by CAS 209542-49-4 and molecular weight 192.21 g/mol.
Medchemexpress LLC DSPE-PEG-FITC | 95.0% | 600 Da (average) | 25 MG
DSPE-PEG-FITC (MW 600) is a fluorescein-labeled PEGylated phospholipid used to introduce surface fluorescence into liposomes and nanoparticles. It is an amphiphilic conjugate that forms micelles in aqueous solution and enables tracking and imaging of lipid-based carriers in biological studies (Ex/Em = 488/525 nm).
- Amphiphilic PEG-lipid that forms micelles in aqueous solution.
- Provides surface fluorescence for liposome and nanoparticle tracking.
- Fluorescein label with excitation/emission 488/525 nm suitable for common fluorescence instruments.
- Average molecular weight about 600 Da for consistent labeling behavior.
- Solid, light yellow material with reported purity ~95.0%.
- Store protected from light; stable frozen in solvent for extended storage.
Avanti Polar Lipids DSPE-PEG 2000 MALEIMIDE, Powder, White, 10 mg
DSPE-PEG(2000) Maleimide is a highly purified, functionalized polyethylene glycol (PEG) lipid designed for advanced research applications in targeted drug delivery. This lipid enables precise conjugation of bioactive molecules to nanoparticle systems, ensuring reliable results in therapies for genetic disorders, cancer, and neurological conditions. Its exceptional purity is confirmed through HNMR analysis, making it a preferred choice for researchers focused on enhancing the specificity and efficacy of drug delivery systems.
- Highly purified PEG lipid for advanced drug delivery
- Facilitates conjugation with thiol-containing bioactive molecules
- Verified structural integrity with no detectable maleimide ring opening
- Application in targeted therapies for genetic disorders and cancer
- Stored at -20°C and shipped with dry ice for optimal stability
- Purity greater than 99% verified by TLC
Medchemexpress LLC DBCO-PEG12-maleimide | 98.0% | 1027.16 g/mol | C52H74N4O17 | 5 MG
DBCO-PEG12-maleimide is a bifunctional polyethylene glycol (PEG12) linker bearing a dibenzocyclooctyne (DBCO) group for strain-promoted alkyne-azide cycloaddition and a terminal maleimide for thiol-specific conjugation. It is designed for catalyst-free click chemistry and selective cysteine conjugation in bioconjugation workflows, linker synthesis, and chemical biology applications.
- Enables copper-free click (SPAAC) reactions with azide-functionalized partners.
- Reacts selectively with thiols via the maleimide to form stable thioether bonds.
- PEG12 spacer improves solubility and provides flexible linker length.
- High purity suitable for sensitive bioconjugation applications.
- Stable when stored dry at recommended low temperatures.